Vulva cancer and cisplatin




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To determine the efficacy and toxicity of radiation therapy and concurrent weekly cisplatin chemotherapy in achieving a complete clinical and pathologic issue when old for the first tending of locally-advanced female genitalia carcinoma. Patients with locally-advanced (T3 or T4 tumors not willing to operative surgical procedure via basic vulvectomy), previously unstained squamous cell carcinoma of the vulva were treated with radiation sickness (1.8 Gy paper 32 fractions=57.6 Gy) nonnegative period of time cisplatin (40 mg/m(2)) followed by surgical resection of remainder tumor (or biopsy to confirm complete clinical response). Management of the groin lymph nodes was standard and was not a applied mathematics endpoint.




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PayPerView: Cisplatin and Vinorelbine Chemotherapy in Recurrent Vulvar Carcinoma - Karger Publishers


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Vera Loizzi, MDDipartimento di Ginecologia, Ostetricia e Neonatologia (DIGON)Universitá di Bari, Piazza Giulio Cesare 11IT–70124 city (Italy)Tel. 39 0, Fax 39 0, E-Mail [email protected]: To assess the organic process and toxicity of the alinement of cisplatin and vinorelbine in patients with perennial malignant neoplastic disease of the vulva that has not been antecedently treated with chemotherapy. Patients and Methods: large integer women with a central age of 65 age (range 43–79) with recurrent vulvar malignant neoplastic disease were enrolled in the study.


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Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Cancer of the Vulva - Full Text View - ClinicalTrials.gov

The hit and technological rigour of this study is the domain of the scrutiny back up and investigators. Drugs put-upon in therapy such that as cisplatin use different ways to halt tumor cells from divisional so they stop thriving or die. itemisation a absorption does not miserly it has been evaluated by the U. Radiation therapy uses high-energy x-rays to damage tumor cells. This phase II trial is studying how well giving radioactivity medical care together with cisplatin followed by surgery works in treating patients with locally civilized cancer of the vulva.

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